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RPManager can submit to a number of rendering managers - Backburner, Deadline, Qube, Rush, Smedge, Royal Render (from the royal render end). You can pick the submission system from the RPManager Preferences dialog, there is a dropdown at the bottom right.
It also supports end-user customised submission, allowing you to install your own scripted submission system, including UI, within RPManager - allowing extensive control over the way your jobs are submitted.
Both Qube and Deadline 6 submission use this external submission setup, (which also means you can customise them) and the are accessed via these steps (using Deadline 6 setup as an example):
If you would like information about how to write your own submission that integrates into RPM email rpmanager@rpmanager.com, or examine either the Qube or Deadline 6 submission script.